Research on nosocomial pulmonary infection in elderly cerebral infarction patients

Abstract

Objective To explore the incidence of nosocomial pulmonary infection in elderly patients with cerebral infarction and its prognosis.Methods Six hundred and sixty-nine patients with cerebral infarction were divided into elderly group (384 cases,≥75 years) and control group (285 cases,40-74 years).Logistic regression analysis was used to research the risk factors for pulmonary infection.According to in-hospital heart disease,neurological damage and hospital death,the prognosis of patients in elderly group was analyzed.Results The proportion of female patients,and patients with hypertension,atrial fibrillation and congetive heart disease in elderly group was significantly higher than that in control group,the incidence of patients with nosocomial pulmonary infection was significantly higher than that in control group,the proportion of patients with smoking and diabetes was lower than that in control group,there were significant differences (P ＜ 0.05 or ＜ 0.01).The proportion of patients with high cholesterol,ischemic heart disease,peripheral arterial disease between 2 groups had no significant difference (P ＞ 0.05).Logistic regression analysis showed that diabetes and smoking were independent risk factors for nosocomial pulmonary infection (P ＜ 0.05).The proportion of patients with the United States National Institutes of Health Stroke Scale(NIHSS) score 11-15 scores in elderly group was higher than that in control group[33.59％(129/384) vs.25.96％(74/285)],there was significant difference (P ＜ 0.05),but the proportion of patients with other NIHSS score had no significant difference (P ＞ 0.05).The proportion of patients with cardioembolism in elderly group was higher than that in control group (x2 =4.38,P ＜ 0.05),the proportion of patients with large artery atherosclerosis was lower than that in control group (x2 =4.57,P ＜ 0.05).The complication rate of in-hospital heart disease,the proportion of patients with severe nerve dysfunction (modified Rankin score ≥ 2 scores) and hospital mortality in elderly group was significantly higher than that in control group,there was significant difference (P ＜ 0.01).Conclusions Nosocomial pulmonary infection is more common in elderly patients with cerebral infarction,and prognosis may be even worse.Prevention and control of pulmonary infection is very important for elderly patients with cerebral infarction. Key words: Aged; Stroke; Prognosis; Pulmonary infection