Abstract
Objective: This study is to analyze correlation between traditional Chinese medicine (TCM) syndrome distribution characteristics and prognosis of hypertensive intracerebral hemorrhage (HICH) operation. Methods: In this study, a total of 150 patients who had received HICH operation from April, 2017 to December, 2020 in our hospital and conformed to inclusion standards were selected. According to classification of TCM syndromes, amount of bleeding of patients was recorded through multiple radiological technologies, baseline information was collected, and prognosis was investigated. The final event was long-term follow-up visit of all-cause mortalities. Moreover, correlation between prognosis and TCM syndromes was analyzed. Results: It found through investigations that there are no statistically significant differences in composition ratio of TCM syndromes among patients with different genders and different age ranges (P > 0.05). Among so many TCM syndromes, bleeding amount of patients with declining vitality and distraction is the highest, while bleeding amount of patients with stirring wind due to yin deficiency is the lowest. With respect NIHSS scores, the patients with declining vitality and distraction show the highest NIHSS scores at admission and 10 d of the course of the disease, followed by patients with upward disturbance of wind-fire. There are statistically significant differences among these two groups (P < 0.05). In this study, follow-up visits are performed to all 150 patients and the average follow-up visit time ranges within 2 - 15 months. A total of 13 deaths are reported. Number of all-cause deaths has statistically significant differences among different syndromes (P < 0.05). Conclusions: Evolutionary characteristics of TCM syndromes of HICH are manifested by development from evidence-based symptoms to deficiency syndromes. Different syndromes are correlated with prognosis of patients. On the one hand, this can be used as an objective index for TCM syndrome classification. On the other hand, this is conducive to judge prognosis recovery of patients and to apply the corresponding symptomatic treatment.
Highlights
According to classification of traditional Chinese medicine (TCM) syndromes, amount of bleeding of patients was recorded through multiple radiological technologies, baseline information was collected, and prognosis was investigated
Hypertensive intracerebral hemorrhage (HICH) generally refers to patients who have spontaneous Intracerebral Hemorrhage combined with hypertension
TCM syndromes of hypertensive intracerebral hemorrhage (HICH) develop from evidence-based symptoms to deficiency syndromes
Summary
Hypertensive intracerebral hemorrhage (HICH) generally refers to patients who have spontaneous Intracerebral Hemorrhage combined with hypertension. It is characteristic of relatively high morbidity, disability rate and fatality, and it is a great threat to physical health and quality of life of patients [1]. Correlation between distribution characteristics of TCM syndromes and prognosis of patients with HICH still remains unknown [2] [3]. Whether there’s a correlation between distribution characteristics of TCM syndromes and prognosis of patients was determined through a statistical analysis of clinical data. Results were conducive to make reasonable prognosis of patients after assessment and provide new ideas and theories for treatment of HICH.
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