Abstract
MicroRNAs (miRNAs), which are endogenous small noncoding RNAs, mainly regulate the expression of many target genes at the post-transcriptional and(or)translational levels. Aberrant expressions of several miRNAs were found in a large variety of neoplasms, including hepatocellular carcinoma (HCC). Previous studies have shown the existence of a large amount of stable miRNAs in human serum, which have laid the foundation for studying the role of serum miRNAs in the diagnosis and prognosis of HCC.(Chin J Lab Med, 2017, 40: 72-76) Key words: Liver neoplasms; Carcinoma, hepatocellular; MicroRNAs; Biological markers
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