Abstract

Ribosomal protein L23 is a new target for gene therapy of cancer. It participates in tumor progression by activating p53, inactivating murine double minute 2, regulating the carcinogenic activity of c-Myc, inducing the multi-drug resistance, and affecting the biologic behaviour of tumors. Generally, it′s considered to be a potential prognostic factor in human cancers. Key words: Neoplasms; Genes, p53; Genes, myc; Drug resistance, multiple; Ribosomal protein L23

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