Abstract

The detection of the renal artery stenosis in hypertensive patients can be a signal of systemic arterial atherosclerosis. To identify and characterize clinical-epidemiologically the hypertensive patients with renal artery stenosis, evaluating factors of cardiovascular risk and presence of symptomatic multiarterial atherosclerotic. Were selected the hypertensive patients who were assisted at the Nephrological Clinic of Universidade Federal do Triângulo Mineiro (UFTM) between 2000-2010, with diagnosis of renal artery stenosis of atherosclerotic etiology. Epidemiological data were evaluated (gender, age, ethnicity), factors of cardiovascular risk (diabetes, hypercholesterolemia, hypertriglyceridemia, tabagism, metabolic syndrome), information on hypertension (time of diagnosis, family report, number of used medicines), previous cardiovascular events (acute myocardial infarctation, ischemic stroke, peripheral arterial disease). Blood pressure levels, global cardiovascular risk and Score Framingham were stratified. Casuistry of 30 patients, feminine majority (73.3%), average of 66 year-old age, 86.67% white, medium time of hypertension of 19.94 years, 89.92 without family report, 13.8 with diabetes, 65.51% smoking, 17.25% hypertriglyredemia, 62.06% with hypercholesterolemia and 66.7% with metabolic syndrome. Average number of medicines in use: 3.26. Dominant right-sided renal artery stenosis separately (46.7%) and in proximal third (56.7%). High creatinine levels in 40% of the patients. As for the hypertension phase, majority phase 2 (47%) and 73.3% with high global cardiovascular risk. Average Framingham Score of 13%. 66.7% presented atherosclerotic disease in another place, being infarctation the main one (53.3%). The most common correlation was with acute myocardial infarctation, what implicates in the search of the coronary compromising to the diagnosis of renal artery stenosis in hypertensive patients to try avoid future damages to the patient.

Highlights

  • The detection of the renal artery stenosis in hypertensive patients can be a signal of systemic arterial atherosclerosis

  • The most common correlation was with acute myocardial infarctation, what implicates in the search of the coronary compromising to the diagnosis of renal artery stenosis in hypertensive patients to try avoid future damages to the patient

  • The 2 main causes of renal artery stenosis that lead to renovascular hypertension (RVHT) are atherosclerosis, which is responsible for 90% of cases, and fibromuscular dysplasia, corresponding to less than 10% of cases.[3,4]

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Summary

Introduction

The detection of the renal artery stenosis in hypertensive patients can be a signal of systemic arterial atherosclerosis. Epidemiological data were evaluated (gender, age, ethnicity), factors of cardiovascular risk (diabetes, hypercholesterolemia, hypertriglyceridemia, tabagism, metabolic syndrome), information on hypertension (time of diagnosis, family report, number of used medicines), previous cardiovascular events (acute myocardial infarctation, ischemic stroke, peripheral arterial disease). Multiarterial atherosclerotic disease in hypertensive patients impairment occurs most frequently in the coronary, renal, carotid, and iliac-femoral arteries.[5,6] Risk factors for its development, such as hypertension, advanced age, diabetes mellitus, and dyslipidemia, are the same for these various sites, and the presence of atherosclerosis in several sites is not an uncommon finding.[4,6] According to some studies, the link between RVHT of atherosclerotic origin and multiartery atherosclerotic disease is common; only 1 concurrent arterial bed has been assessed in each study.[4,5,6,7,8]

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