Research of Clinical Features about first-ever ischemic stroke in small-artery occlusion patients

Abstract

Objective Small-Vessel Occlusion is a common etiology of ischemic stroke. In this study, we investigate the Clinical Features of first-ever ischemic stroke in small-artery occlusion patients. Methods All the information were provided by the database of patients with acute ischemic stroke admitted to the Department of Neurology, Shanghai Yueyang Hospital, Shanghai, China, from January 2011 to January 2016. According to the TOAST criteria, 172 first-ever acute ischemic stroke patients were divided into SAO group (small-artery occlusion) and Non-SAO group. We compared the differences of two groups in risk factors, clinical manifestations and laboratory data. Results In SAO group, family history of stroke (14.2% vs 4.5%， P = 0.045) and diabetes (33.0% vs 18.2%， P = 0.034) were more common， and the proportion of patients with atrial fibrillation (7.6% vs 16.7%, P = 0.009) was less common when compared to those in Non-SAO group. Paralysis (49.4% vs 77.8%，P = 0.002), speech disorder (55.4% vs 80%， P = 0.006)and pulmonary infection (13.2% vs 33.3%, P = 0.002)were less common， and the severity of the disease is mild according to MIHSS, BI and MRS in the SAO group (P = 0.000； P = 0.000； P = 0.009). And the contents of WBC、GOT、LDL、CRP、D-Di was significantly lower in SAO group than those in Non-SAO group. Conclusion There was significantly difference in risk factors, clinical manifestations and laboratory data between SAO group and Non-SAO group.