Research of chemical and toxic properties of humic acids of low-moor woody-grassy type of a peat in Tomsk Region

M V Belousov,A V Matveyenko,R R Akhmedzhanov,M V Gostischeva,M S Yusubov

doi:10.20538/1682-0363-2009-4(2)-27-32

Abstract

In article results of research of a chemical structure of humic acids of low-moor woody-grassy type of peat of Tomsk Region are resulted by methods of the elemental analysis and infra-red spectroscopy. In this work results of toxicological research of humic acids also are described: acute toxicity, pathomorphology and flow properties of blood. It is shown, that humic acids of low-moor woody-grassy type of peat represent connection with a high share aliphatic fragments submitted long connected by circuits, have a small degree benzenoid, contain active oxygen and itrogen-containing functional groups (carboxylic, hydroxyl, amides, amino groups). It is established, that humic acids at intragastric introduction are nontoxic substances. At intraperitoneal introduction of lethal dozes, the destruction of animals comes from acute intimate insufficiency, thus the cause of acute infringement hemodynamics can be negative influence of humic acids on flow properties of blood.

Highlights

Проведены исследования химического строения гуминовых кислот низинного древесно-травяного торфа Томской области методами элементного анализа и инфракрасной спектроскопии
In article results of research of a chemical structure of humic acids of low-moor woody-grassy type of peat of Tomsk Region are resulted by methods of the elemental analysis and infra-red spectroscopy
That humic acids of low-moor woody-grassy type of peat represent connection with a high share aliphatic fragments submitted long connected by circuits, have a small degree benzenoid, contain active oxygen and itrogen-containing functional groups

Summary

Экспериментальные и клинические исследования

Белоусов М.В.1, Ахмеджанов Р.Р.2, Гостищева М.В.1, Юсубов М.С.1, Матвеенко А.В.1. Belousov M.V., Akhmedzhanov R.R., Gostischeva M.V., Yusubov M.S., Matveyenko A.V. Проведены исследования химического строения гуминовых кислот низинного древесно-травяного торфа Томской области методами элементного анализа и инфракрасной спектроскопии. In this work results of toxicological research of humic acids are described: acute toxicity, pathomorphology and flow properties of blood It is shown, that humic acids of low-moor woody-grassy type of peat represent connection with a high share aliphatic fragments submitted long connected by circuits, have a small degree benzenoid, contain active oxygen and itrogen-containing functional groups (carboxylic, hydroxyl, amides, amino groups). That humic acids of low-moor woody-grassy type of peat represent connection with a high share aliphatic fragments submitted long connected by circuits, have a small degree benzenoid, contain active oxygen and itrogen-containing functional groups (carboxylic, hydroxyl, amides, amino groups) It is established, that humic acids at intragastric introduction are nontoxic substances. Цель настоящего исследования — изучение химического строения и токсических свойств гуминовых кислот, полученных из низинного древесно-травяного вида торфа месторождения «Клюквенное» Томского района Томской области

Материал и методы

Результаты и обсуждение

Атомное отношение

Параметры острой токсичности гуминовых кислот при внутрибрюшинном введении мышам

Показатели выживаемости крыс при внутрижелудочном введении ГК

ГК Трентал Декстран