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Abstract
Most pathological processes in the human body of various origins are accompanied by signs of inflammation, namely: swelling (tumor), redness (rubor), fever (calor), pain (dolor) and dysfunction of a particular organ or system (functio laesa). The pathological process of inflammation is a response to the action of external or internal phlogogenic agents. Today, nonsteroidal anti-inflammatory drugs are the main drugs for the treatment of inflammatory processes. Therefore, one of the key tasks of pharmacy is the development and research of herbal anti-inflammatory drugs. One of the promising plants that has anti-inflammatory action is Eryngium planum. These are plants that belong to the family Apiaceae (Umbelliferae) and contain a large number of biologically active substances.
Highlights
Today, first-line drugs in the treatment of inflammatory processes are nonsteroidal anti-inflammatory drugs (NSAIDs)
Nonsteroidal anti-inflammatory drugs are the main drugs for the treatment of inflammatory processes
The positive pharmacological effect of NSAIDs is accompanied by a number of side effects
Summary
First-line drugs in the treatment of inflammatory processes are nonsteroidal anti-inflammatory drugs (NSAIDs). Acute toxicity was studied in white adult mice of both sexes, which were injected with flat extracts. The model of formalin edema of the hind paw of white rats was used to determine the anti-inflammatory activity of flat extracts.
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