Abstract

In today's medical system, limited resources are available for patient care. For this reason, it is important to evaluate the outcomes of various interventions to ensure that patients are receiving the most efficient and best available care. Recently, clinicians and payers are recognizing that physiological measures do not necessarily relate to function, and functional outcomes need to be measured independently.1–3 Measuring health related quality of life (HRQL) is one method of evaluating functional outcomes. HRQL is commonly assessed through self or interviewer administered questionnaires, and may be discriminative (evaluating cross-sectional differences between patients at a single point in time) or evaluative (measuring longitudinal changes within patients over a period of time).1 For a HRQL instrument to be effective and useful it must be valid, reliable, responsive, and interpretable.4 In general, disease specific measures of HRQL are more responsive than generic tools and may have more face validity to both the patient and clinician.1,5 The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess HRQL in patients with chronic respiratory disease.5 The developers suggest that this tool be used to evaluate the effects of treatment in clinical trials as well as in clinical practice.2 As it is so widely used, it is important to understand the psychometric properties of this tool in order to truly understand its effectiveness and practical application. This paper describes the current research regarding the reliability, validity, responsiveness, minimally clinical important difference, and suggested use of the Chronic Respiratory Disease Questionnaire in clinical practice.

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