Abstract

MUC4,a member of transmembrane matin family,is expressed in many kinds of tissues,organs and secretions.In addition,aberrant expression of MUC4 has been reported in a variety of carcinomas.MUC4 is a kind of multi-function proteins,and is related to the growth,invasion and metastasis of tumors.All of these features of MUG4 strongly support its role as a potential candidate for diagnosis and therapy of carcinoma. Key words: Pancreatic neoplasms; Mucins; Signal transduction

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