Research advances in biomarkers for early diagnosis of acute aortic dissection

Abstract

Acute aortic dissection (AAD) is a potentially catastrophic cardiovascular disease, with significant morbidity and mortality, and it remains a challenge to diagnose and treat. Survival rate has been shown to be directly related to prompt diagnosis and precise management, it is necessary for early diagnosis and treatment. However, diagnosis of the disease relies heavily on various imaging techniques, remaining time-consuming and difficult to obtain. Nevertheless, the application of biomarkers provides a new direction for the diagnosis of AAD. Therefore, the application of biomarkers with high specificity and sensitivity contribute to optimal treatment to reduce the mortality rate is the current research direction. This article was to summarize the domestic and abroad research advances which focused on the biomarkers and progress of aortic dissection. Key words: Aorta; Aneurysm, dissecting; Biological markers; Early diagnosis