Abstract
A new member of the anthracycline group of antibiotics named requinomycin has been isolated from a strain of Streptomyces filamentosus which had been screened for anti-phage activity. The antibiotic was obtained as yellow crystals, whose molecular formula was assigned to C40H54N2O16. It inhibits the reproduction of phage f 2 in E. coli S-26, the transfer of R-factors between E. coli strains, the growth of Gram-positive bacteria and the growth in vitro of YOSHIDA rat sarcoma cells. Requinomycin resembles aklavin but they are apparently different in antibiotic activity against E. coli B and stability to acid hydrolysis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
