Abstract
Ciclopirox is an anti-mycotic drug, used topically, that belongs to the hydroxypyridone molecular class and is not linked to azole drugs or other anti-fungal medication. Ciclopirox was first designed to treat vaginal candidiasis and fungal skin infections, and it is now widely used for these conditions. Drug repurposing is a method for discovering new applications for authorized or experimental medicines that go beyond the original medical indication. Ciclopirox received acknowledgement as repurposed anti-cancer agent (anti-bladder cancer, anti-Ewing sarcoma, anti-pancreatic cancer, hematologic malignancy inhibitor, proliferating cell lines inhibitor, etc.) owing to multiple therapeutic excellencies, where numerous signaling pathways plays role in treating diverse cancer forms. This review article paved a new way by eventually opening newer possibilities for the enthusiastic (medicinal)-chemists, pharmacologists, and researchers of allied branches to design better drugs, repurpose this drug further, and finally use it clinically against various forms of proliferating diseases like cancer.
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