Abstract

For the past several months there has been sustained human-to-human transmission of a novel strain ofavian influenza A with genetic components of human influenza in several countries around the world. Your community was first affected three weeks ago and since then there have been over 500 cases and 50 deaths. Oseltamivir phosphate is the only drug that may effectively reduce mortality of ill patients and limit infection of exposed persons. However, supplies of oseltamivir are limited, and hospitals across the country are independently making decisions to govern allocation of antivirals within their institutions. In your community, the five major academic medical centers have recently established five different protocols regarding prioritization of access to care:

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