Reproductive pattern in consanguineous and non-consanguineous marriages in La Cabrera, Spain

Abstract

Among determinants of the structure of human populations, consanguineous marriages can be useful in determining to what extent they influence the genetic structure of the population. This knowledge may be gained by comparing the reproductive performance of related and non-related couples. The population studied, La Cabrera, is a mountainous region in the Leon province (north-western Spain). It includes four neighbouring municipalities with similar geographic, climatic and ecological features with 37 parishes occupying an area of 784.2 km(2), of which only 1.5% is arable. The number of inhabitants remained stable from 1887 (9526 inhabitants) to 1960 (8984), when due to emigration it began to decrease. The average inbreeding coefficient (alpha) for the period 1880-1989 (up to third degree) was 4.82 x 10(-3). The objective of this analysis was to evaluate the possible factors determining the differences between consanguineous and non-consanguineous families residing in La Cabrera during the period 1880-1959. To study the structure and dynamics of each couple, families were reconstituted for the period 1880-1959 using demographic data corresponding to births, deaths and marriages obtained from parish registers. This procedure provided information on each couple's reproductive history through information concerning the mates' deaths as well as their offspring's births and deaths. Principal component analysis revealed the existence of three factors that together explained 57% of the reproductive pattern variability of La Cabrera. The first component (eigenvalue: 3.56) correlated positively with the number of live births and with the duration of the reproductive period. Component II (eigenvalue: 1.54) had a positive correlation with variables describing the beginning of the marital union, and with those indicating its ending. Finally, component III (eigenvalue: 1.13) reflected a negative association with the two variables that described neonatal and post-neonatal mortality. The above demographic variables represented the reproductive process in La Cabrera adequately. Fertility was the variable that offered the best explanation of the reproductive pattern (32%), followed by the marital structure (13%) and the infant mortality (12%). In the La Cabrera population, consanguinity appears as a socio-cultural process that affects the reproductive dynamic. Consanguinity modifies the marital structure and alters the reproductive pattern, prolonging the reproductive period, which results in a greater number of offspring. Lower infertility rates and the possible compensatory effect for infant mortality may reflect biological factors making the wife's reproductive period more efficient.