Reproductive outcomes of ectopic pregnancy with conservative and surgical treatment

Abstract

Review question / Objective: The objective of this study was to investigate the natural pregnancy outcomes(IUP,REP) of ectopic pregnancy patients by comparing MTX versus surgery, MTX versus salpingostomy, MTX versus salpingectomy, salpingostomy versus salpingectomy, MTX versus expectant treatment. Condition being studied: Ectopic pregnancy(EP) remains one of the most common gynecological emergencies and a leading cause of maternal death in early pregnancy, Increase infertility and repeat ectopic pregnancy. Surgical treatment is considered the gold standard treatment, but with advances in early diagnosis, such as β -hCG levels and transvaginal ultrasound, EP can be diagnosed in the early stage, and the emergency operation rate and mortality rate of ectopic pregnancy are significantly reduced, and some patients can choose to expectant treatment or medical treatment, such as methotrexate (MTX). Naveed AK et al. suggests that expectant treatment is as safe and effective as MTX in EP patients with stable hemodynamic conditions and decreased or low β -hCG levels. The overall success rate of MTX is reported to be as high as 90% when choosing good indications. There is an increasing attention to reproductive outcomes for EP patients, especially for those who want to have a child, so it is crucial to clarify the impact of each treatment modality on natural pregnancy outcome.