Reproductive outcome after hysteroscopic metroplasty in women with septate uterus and otherwise unexplained infertility

Abstract

Objective To evaluate the reproductive outcome of hysteroscopic metroplasty performed in women with septate uterus and otherwise unexplained primary infertility. Design Prospective, observational study. Setting Tertiary center for reproductive medicine. Patient(s) Sixty-one patients with uterine septa and otherwise unexplained primary infertility. Intervention(s) Hysteroscopic division of the uterine septum. Main outcome measure(s) Reproductive outcome after hysteroscopic metroplasty. Result(s) Of 61 women, 25 (41%) conceived within 8–14 (mean 11.2) months after hysteroscopic metroplasty. Of these, 18 (29.5% of the total group) had live births (13 carried to term and 5 had preterm deliveries), and 7 (11.5% of the total group) had spontaneous abortions. Cervical cerclage was performed in 9 women; only 1 (11.1%) of these patients and 4 (44.4%) of the 9 who did not have a cerclage had preterm deliveries. Twelve of the 18 women (66.6%) who had live births were delivered by cesarean section. Conclusion(s) Women with uterine septum and otherwise unexplained infertility might benefit from hysteroscopic metroplasty.