Abstract
The article presents a review of retrospective cohort studies of fertility and pregnancy outcomes in women with celiac disease. The article presents the results of our own observations of obstetric and gynecological anamnesis 17 women with celiac disease for the period from 2016 to 2020. Materials and methods. Information collected from patients was analyzed in retrospective cohort studies. Patients with celiac disease and healthy women of reproductive age were included in these studies. Result. The ability of IgA and IgG class antibodies to tissue transglutaminase to disrupt trophoblast invasiveness and endometrial endothelial cell differentiation underlies the failure of early placentation in celiac disease. In the case of the latent course of celiac disease there is an increased risk of recurrent miscarriages and preterm births, impaired growth of the fetus with low birth weight. Conclusion. Given the high percentage of unidentified diagnoses, it is extremely important to identify risk groups for timely treatment and prevention of complications.
Highlights
Given the high percentage of unidentified diagnoses, it is extremely important to identify risk groups for timely treatment and prevention of complications
The article presents a review of retrospective cohort studies of fertility and pregnancy outcomes
The article presents the results of our own observations
Summary
И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Российская Федерация, 191015, ул. В. Репродуктивные изменения у женщин с целиакией. Орешко Людмила Саварбековна, д.м.н., профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. Рысса Семенова Елена Анатольевна, к.м.н., ассистент кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. Рысса Алиева Гюнель Чингизовна, студентка 4 курса Басюл Октавия Власовна, студентка 5 курса. В статье представлен обзор ретроспективных когортных исследованиях изучения фертильности и исходов беременности у женщин с целиакией. В статье изложены результаты собственных наблюдений акушерско-гинекологического анамнеза у 17 женщин с целииакией за период с 2016 года по 2020 год. В случае латентного течения целиакии отмечено повышение риска повторных выкидышей и преждевременных родов. Учитывая высокий процент неустановленных диагнозов, крайне важно выявление групп риска с целью своевременного лечения и профилактики осложнений.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
