Abstract

The reproductive capacity of isologous P–388 leukaemic cells has been determined in vivo after irradiation with fast neutrons from the M.R.C. cyclotron, Hammersmith Hospital. When tumour-bearing donor animals are irradiated at 10 cm depth in tissue-equivalent phantom material, using a relatively narrow fast neutron beam, the results are indistinguishable from results when donor animals are irradiated in air using a wide neutron beam. Implications of this finding for radiotherapy of human tumours are discussed.

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