Abstract

Background: After the failure of medical treatment, the surgery of chronic rhinosinusitis (CRS) is planned according to endoscopic and paranasal sinus computed tomography (CT) findings. Objective: The aim of this prospective study was to evaluate whether this study method might be eligible in studies aiming at radiation dose reduction. Sinus CT scans were chosen as a model because of the high variation of the radiological anatomy of surgically important sinonasal structures. We hypothesized that 3 mm-slice-thick reconstruction CT had poor reproducibility. Methods: 59 CRS patients underwent routine multi-detector sinus CT (CTMD). CT3mm was reconstructed from CTMD data-sets. Lund-Mackay (LM) scores and 43 other structural parameters were analyzed blinded. Agreement was studied between CTMD and CT3mm (intra-observer reproducibility), and between three observers (inter-observer reproducibility) by using Cohen’s kappa. Results: The inter-observer agreement was moderate (kappa 0.4 - 0.6, p 3mm scans. The intra-observer reproducibility of CT3mm scans was very good in most structures, however, it was poor in important structures such as frontal and spheno-ethmoid recess, lamina papyracae, and location of optic nerve or anterior ethmoidal artery. The grade of surgeon’s confidence of CT3mm in comparison to CTMD was lower (kappa 0.2 - 0.4, P < 0.05). Conclusion: This methodology might have some use in studies aiming at radiation dose reduction. As was expected, 3 mm-slice-thick reconstruction CT had poor reproducibility and surgeon’s confidence. More recent methods such as cone beam computed tomography scans have nowadays more relevant dose reduction potential.

Highlights

  • Chronic rhinosinusitis (CRS) is a common, multifactorial and variable disease with a prevalence of around 10% - 16% [1]

  • The mean age was 43 (13 - 77) years by the time of taking the computed tomography (CT) scans. 54.2% of patients underwent sinonasal operation within a year after the CT scans were performed (Table 1). Of these patients that were operated at the time of CT scans, 7 (21.9%) underwent revision sinonasal surgery in average 3 years later. 47.5% of patients reported suffering from diseases with regular need of medications

  • This study was carried out to evaluate whether the used method would be eligible when studying radiation dose reduction potential

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Summary

Introduction

Chronic rhinosinusitis (CRS) is a common, multifactorial and variable disease with a prevalence of around 10% - 16% [1]. The main findings in CRS are mucosal changes within the osteomeatal complex and/or sinuses. After the failure of medical treatment, the surgery of chronic rhinosinusitis (CRS) is planned according to endoscopic and paranasal sinus computed tomography (CT) findings. Sinus CT scans were chosen as a model because of the high variation of the radiological anatomy of surgically important sinonasal structures. Methods: 59 CRS patients underwent routine multi-detector sinus CT (CTMD). Agreement was studied between CTMD and CT3mm (intra-observer reproducibility), and between three observers (inter-observer reproducibility) by using Cohen’s kappa. Results: The inter-observer agreement was moderate (kappa 0.4 - 0.6, p < 0.01) in the majority of structures of CT3mm scans. The intra-observer reproducibility of CT3mm scans was very good in most structures, it was poor in important structures such as frontal and spheno-ethmoid recess, lamina pa-

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