Reproducibility of 1H MR spectroscopy of hip bone marrow at 3 tesla

Abstract

To assess the reproducibility of fat content (FC) values in five different anatomical areas of proximal femur by the means of (1)H 3 Tesla MR spectroscopy and to evaluate if any statistical difference exists when comparing right side to left side FC values in the same individual. Thirty-three volunteers underwent unilateral (1)H MR spectroscopy of the hip. From 1 to 4 weeks later, they repeat the MR examination of the same hip to assess the reproducibility of the technique. Fifteen other volunteers underwent a bilateral (1)H MR hip spectroscopy to compare right and left side FC values. The reproducibility of (1)H MR spectroscopy was high in all the anatomic areas considered, ranging from 0.90 to 0.98. No statistically significant difference was found when the fat content values on the right side were compared to those on the left side. (P > 0.16). The 3 Tesla (1)H MR spectroscopy of hip bone marrow permitted highly reproducible fat content values in all the five anatomic areas examined. No statistical significant difference existed when comparing fat content values of the right side to those of the left side in the same individual.