Abstract
Abstract Anti-Cw (C Willis) is a low-frequency immunoglobulin against red cell antigen Cw in the Rhesus (Rh) blood group system. Anti-Cw can either be naturally occurring or develop as a result of red blood cell sensitization through transfusion or during pregnancy, and is rarely associated with clinically significant hemolytic disease of the fetus and newborn. However, anti-Cw, being a low-frequency antigen, is not always included in the commercial antibody screening panels and also not phenotyped for in-house pooled red cells used for single-cell indirect antiglobulin testing for blood donors in various blood centers. Here, we report a case of a whole blood donor who was identified with an anti-Cw antibody.
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