Abstract

BackgroundMalaria is an important cause of morbidity and mortality in malaria-endemic areas. Indoor residual spray is an effective intervention to control malaria, but high community-level coverage is needed to maximize its impact.Methods and resultsUsing thirty-four two-stage cluster surveys (e.g., demographic and health surveys) and lot quality assurance sampling, indoor residual spray was estimated at the community level (i.e. enumeration-area) across sub-Saharan Africa since 2010. For communities receiving indoor residual spray a logistic regression predicted whether community-level coverage exceeded 50% or not. Household-level coverage was equitable both in terms of wealth and urban/rural, with poorer and rural houses more likely to be sprayed than richer and urban houses. Coverage of indoor residual spray at the community level is poor across the continent, with 54% of communities receiving the intervention not reaching 50% coverage. Having >50% coverage at the community-level was not associated with increasing the number of houses sprayed in the country.ConclusionsImplementation and monitoring of indoor residual coverage at small geographical scales need to improve greatly to receive maximum benefit of the intervention.

Highlights

  • Malaria is an important cause of morbidity and mortality in malaria-endemic areas

  • While malaria is found throughout tropical regions of the world, sub-Saharan Africa carries the greatest malaria burden, with 90% of the estimated 212 million worldwide cases of malaria occurring in Africa in 2015 [1]

  • Participants indoor residual spray (IRS) was not measured in Multiple Indicator Cluster Surveys (MICS)

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Summary

Introduction

Indoor residual spray is an effective intervention to control malaria, but high community-level coverage is needed to maximize its impact. Since 2000, malaria transmission in sub-Saharan Africa has been greatly reduced [3], primarily through the scale-up of insecticide-treated mosquito nets (ITN) [4]. Today ITNs are typically the primary intervention to control malaria vectors in malaria-endemic countries, while indoor residual spray (IRS) is most often used as a supplemental vector control if used at all. Malaria control programmes may consider combining IRS and ITNs to increase impact beyond that obtained by a single intervention. It remains unclear whether IRS in the context of high ITN coverage decreases malaria

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