Abstract
We have reported two cases of TAKAYASU'S syndrome, in which skin complication of tuberculide- or tuberculoderma-like eruptions are observed. Thirty-three and 40 year-old female patients with characteristic clinical picture of pulseless disease have developed during their clinical course, papulonecrotic tuberculide-like exanthema on her forearms and erythema nodosum-like eruptions in her shins in the former and tuberculoderma-like pyoderma on her left forearm and both shins in the latter. Skin biopsy has been done on these eruptions, which indicated nonspecific proliferative inflammation and the culture of tubercle bacilli from these specimen was negative. It has been suggested that the immunoallergic reaction would be well responsible in pathogenesis of both aortic lesion and skin eruptions, most likely based on tuberculosis allergy.
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