Abstract
We present a report of a workshop sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) on the genetics of basal serum IgE levels, which was held September 27 and 28, 1979, in Baltimore. Ten investigators including immunologists, geneticists, and statisticians met to discuss laboratory measurements of total serum IgE levels, environmental factors affecting basal IgE levels, methods of analysis of family data, results of recent studies, and the need for further studies. The main conclusions were that additional studies are needed to investigate environmental factors affecting IgE levels, confirm the presence of a locus regulating IgE levels, and map the locus to a specific chromosome in humans.
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