Abstract
Auto-erythrocyte Sensitization Syndrome, also known as Gardner Diamond syndrome, is characterized by spontaneous painful and repetitive purpura. Here, we report two women aged 14 and 18 years who were diagnosed with auto-erythrocyte sensitization syndrome by typical laboratory, clinical, histopathological features and intradermal skin test. Burning and itching were the major complaints associated with spontaneous ecchymosis. The frequency of attacks in the patient using a specific serotonin re-uptake inhibitor due to migraine was significantly higher than the patient who did not receive psychiatric treatment. It was concluded that careful psychiatric evaluation is important for effective treatment of the disease.
Highlights
Auto-erythrocyte Sensitization Syndrome (OSS), known as Gardner Diamond syndrome, is characterized by spontaneous painful and repetitive purpura
In this report we present two rare cases with autoerythrocyte sensitization syndrome
OSS, known as psychogenic purpura, is a rare condition characterized by the formation of spontaneous and painful skin lesions that develop into ecchymosis following episodes of severe physiological or psychological stress [3]
Summary
Auto-erythrocyte Sensitization Syndrome (OSS), known as Gardner Diamond syndrome, is characterized by spontaneous painful and repetitive purpura. In this disease, which often affects young women, lesions can be seen all over the body and are triggered by psychogenic stress or minor trauma [1]. It is thought that the disease is an autoimmune vasculopathy associated with sensitization to erythrocyte membrane containing phosphatidylserine [2]. In this report we present two rare cases with autoerythrocyte sensitization syndrome
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