Abstract
Event Abstract Back to Event Report of the use of topical ozone together with professional oral hygiene procedures in patient with gingival mucous membrane pemphigoid Paola Carcieri1*, Roberto Broccoletti1, Alessio Gambino1, Davide Conrotto1, Mario Carbone1 and Paolo Giacomo Arduino1 1 University of Turin, Department of Surgical Sciences, Oral Medicine Section, Italy Aim. Mucous membrane pemphigoid (MMP) is a heterogeneous group of autoimmune chronic inflammatory, subepithelial blistering disorder, predominantly involving the mucous membranes. It has a female predilection and commonly occurring after the fifth decade of life. The oral mucosa is affected in more than 90% of cases. Even if this condition has been reported as non-plaque induced, effective dento-gingival plaque control sometimes could resolve the gingival inflammation. Ozone is naturally produced by the photo dissociation of molecular oxygen into activated oxygen atoms which then react with further oxygen molecules. This transient radical anion rapidly becomes protonated, which in turn decomposes to an even powerful oxidant, the hydroxyl radical OH. Application of ozone in periodontics comes as a result of its physic-chemical properties. Ozone therapy has a wide range of applications in treating various diseases owing to its unique properties including antimicrobial, immunostimulant, analgesic, detoxicating, bioenergetic and biosynthetic actions. Materials and Methods. A 70-year-old female patient presented with 1-year history of intact blisters in her mouth, which ruptured leaving throbbing ulcers and peeling of the gingiva; she also reported pain and burning sensation while taking hot and spicy foods. A biopsy was performed with MMP evidence. A professional oral hygiene regimen was started to deal with the gingival status associated together with the use of local ozone applications. Severity of pain was detailed using a Visual Analogue Scale (VAS). Patient received non-surgical periodontal therapy, including personalized oral hygiene instructions, and thorough supragingival scaling and polishing with the removal of all deposits and staining. Clinical outcome variables were recorded at baseline and after the intervention and included full-mouth plaque scores (FMPS), full-mouth bleeding scores (FMBS), and the clinical extension of gingival involvement. Results. After finishing the proposed protocol, a significant and statistical reduction was observed for FMPS, FMBS, and clinical gingival involvement, without using any topical or systemic immunosuppressant. Discussion. Professional oral hygiene procedures and non-surgical periodontal therapy, including topical use of ozone therapy, were associated with a prominent improvement of gingival clinical outcomes in this female with exclusive MMP related gingivitis.
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