Report of 7 cases of penile cancer, with its statistical study

Abstract

Seven cases of penile cancer seen in our clinic during the period of eleven years from 1953 to 1963 were reported. A statistical study was made on 264 cases of penile cancer reported to us from main medical facilities in Japan including our 7 cases. The results are as follows.As to our cases;1) During the period of eleven years from 1953 to 1963, 7 cases of penile cancer (0.105%) were seen out of 6, 638 male patients in our clinic.2) All the 7 cases were squamous cell carcinoma pathologically., 3) Circumcision had been performed in 24 cases (9.09%) out of 264. Penile cancer occured within a year after circumcision in 6 cases (25%) out of 24 and within two years in 5 cases (20.85%).4) The 3 cases were treated with total penectomy, radical groin dissection and irradiation. The other 3 cases were treated with partial penectomy and irradiation. A case was treated merely with partial penectomy.Out of 291 cases from main medical facilities in our country, 264 cases were diagnosed histologically. The statistics are as follows.1) Out of 136, 098 male urogenital patients, there were 264 penile cancers among 5, 876 cases of malignant tumor. The penile cancers were 0.193% of all male urogenital patients and 4.49% of malignant tumors.2) The age of these cases ranged from 21 to 94 with the average-53 years.3) As to initial lesions, 127 cases (54.74%) out of 232 were at plans, 42 cases (18.10%) at foreskin, 45 cases (19.39%) at sulcus coronarius, 16 cases (6.89%) at shaft and 2 cases (0.86%) at prepuce, while the lesions of other 32 cases were not described.4) Microscopically 251 cases (95.09%) out of 264 were squamous cell carcinoma, 5 cases (1.89%) basal cell carcinoma, 3 cases (1.13%) adenocarcinoma, 3 cases (1.13%) melanocarcinoma and 2 cases (0.75%) simple carcinoma.5) Metastasis was discovered in 130 (49.28%) out of 264 cases and in 125 cases metastasis in the inguinal nodes.6) As to treatments, 54 cases (21.95%) were treated with total penectomy, radical groin dissection and irradiation, 53 cases (21.54%) with total penectomy and irradiation, 42 cases (17.0%) with total penectomy and radical groin dissection, 38 cases (15.44%) merely with total penectomy. The treatment of other 18 cases was not reported.7) As to the course of 159 cases, 73 cases (45.91%) died within a year after the treatment, 29 cases (18.23%) within two years, 20 cases (12.57%) within three years, 14 cases (8.80%) within four years, 9 cases (5.66%) within five years, and 14 cases (8.80%) were found still alive for more than five years.