Abstract
The French Society of Toxinology (SFET) organized its 27th annual meeting on 9–10 December 2021 as a virtual meeting (e-RT27). The central theme of this meeting was “Toxins: Mr Hyde or Dr Jekyll?”, emphasizing the latest findings on plant, fungal, algal, animal and bacterial toxins during 10 lectures, 15 oral communications (shorter lectures) and 20 posters shared by ca. 80 participants. The abstracts of lectures and posters, as well as the winners of the best oral communication and poster awards, are presented in this report.
Highlights
6 6 CEA, Institut des Sciences du Vivant Frédéric Joliot, Département Médicaments et Technologies pour la CEA, Institut des Sciences du Vivant Frédéric Joliot, Département Médicaments et Technologies pour la
Dendrocnide species contain heretofore-unknown pain-inducing peptides that potently activate sensory neurons and delay the inactivation of voltage-gated sodium channels. These neurotoxins localize to the stinging hairs and are mini-proteins of 4 kDa whose 3D structure is stabilized in an inhibitory cystine knot motif, a characteristic shared with neurotoxins found in spider and cone snail venoms
In this work, exploiting the ability of PnTx-G to be chemically synthesized and radiolabeled, we studied in vivo the toxicokinetics of [3 H]-PnTx-G and its capacity to interact with neuronal and muscle-type nicotinic acetylcholine receptors
Summary
Published maps institutional affiltral with regard to jurisdictional iations. Mr Hyde ber 2021 as aasvirtual meeting (e-RT27). TheThe central theme of this meeting was was or Dr orJekyll?”, Dr Jekyll?”, emphasizing the latest findings on plant, fungal, algal, animal and bacterial emphasizing the latest findings on plant, fungal, algal, animal and bacterial toxins toxins during oral communications (shorter lectures) and 20 posters shared. 10 lectures, 15 oral[15] communications and 20 posters shared by ca.by80ca. The abstracts of lectures and posters, as well as the winners of the best oral communication. The abstracts of lectures and posters, as well as the winners of the best oral communication and and poster awards, presented in this report. Poster awards, are are presented in this report. Toxin tion/activity; toxin receptor/target; toxin structure function/activity; toxin receptor/target; toxin structure
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