Abstract

We much appreciate the forward-looking thoughts and encouragement provided by the authors of the invited commentary on our article. We completely agree that the small number of animals is a major limitation of our experiment. However, as well pointed out in the comment, this was just a first step toward what we believe is the right direction. Although still in its earlier phases of development, the full integration of image-guidance techniques in minimally invasive surgery bears the potential to benefit prostate cancer patients by increasing the precision of surgical procedures. Editorial CommentUrologyVol. 81Issue 2PreviewThe authors of this work demonstrated, in 2 mice with implanted subcutaneous prostate cancers, that an intravenously injected compound targeting prostate-specific membrane antigen (PSMA) allowed visualization of tumor fluorescence using the da Vinci robotic system with Firefly capability (near-infrared fluorescence). Although this study was limited in animal number due to equipment availability, and although there remain many unanswered questions before clinical application could be pursued, the significance of this work should not be dismissed. Full-Text PDF

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