Abstract
Active surveillance (AS) for low-risk prostate cancer is now a widely accepted management option. Yet, the commonly used criteria for AS such as National Comprehensive Cancer Network (NCCN) and University of California San Francisco (UCSF) guidelines have been developed based on variations of serum prostate-specific antigen (PSA) levels and prostate biopsy results. No additional risk stratification is used. Editorial CommentUrologyVol. 81Issue 4PreviewIn the current study, the authors analyze the rates of upstaging and upgrading after radical prostatectomy in African American (AA) and White American (WA) men with prostate cancer who were eligible for active surveillance (AS) at initial diagnosis, according to the University of California San Francisco (UCSF) and National Comprehensive Cancer Network (NCCN) criteria. Nearly 46% of AA men in this study were upstaged and/or upgraded. AA men had a significantly increased probability of upstaging/upgrading and higher rate of adverse clinicopathological features on final surgical pathology compared to WA patients. Full-Text PDF
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