Abstract
We thank Eldeeb and associates for their comments regarding our paper on disorganization of the retinal inner layers (DRIL) as a predictor of visual acuity in eyes with macular edema secondary to vein occlusion. 1 Mimouni M. Segev O. Dori D. et al. Disorganization of the retinal inner layers as a predictor of visual acuity in eyes with macular edema secondary to vein occlusion. Am J Ophthalmol. 2017; 182: 160-167 Abstract Full Text Full Text PDF PubMed Scopus (64) Google Scholar In this paper we assessed DRIL as a potential marker predicting improvement in visual acuity. Specifically, we investigated 2 main study questions: (1) Could change in the extent of DRIL at 4 months predict change in visual acuity at 8 months? and (2) Was change in the extent of DRIL at 8 months associated with change in visual acuity at 8 months? Disorganization of the Retinal Inner Layers as a Predictor of Visual Acuity in Eyes With Macular Edema Secondary to Vein OcclusionAmerican Journal of OphthalmologyVol. 186PreviewWe read Mimouni and associates' article on disorganization of the retinal inner layers (DRIL) with great interest.1 In a study seeking to identify spectral-domain optical coherence tomography (SDOCT) biomarkers of visual acuity (VA) outcomes in retinal vein occlusion (RVO) with macular edema, the authors concluded that of various imaging parameters, only the extent of DRIL at baseline, and its change over 4 months, were independently predictive of VA improvement over 8 months. However, several methodological aspects warrant concern. Full-Text PDF
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