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Abstract

We agree with this assessment and the limitations of our study. Certainly, future prospective studies are needed and they should consider all of these valid points. Of interest, our initial goal was to perform a prospective, randomized study that addressed this issue. However, after careful and extensive literature reviews, we were unable to locate a single study that examined postoperative infections and antibiotic use as a primary outcome while using more contemporary management routines (minimizing both postoperative Foley catheter and prolonged antibiotic use). Thus, we elected to conduct a baseline observational study as an initial attempt to address this question and also to provide data upon which to base power and sample size calculations for future prospective studies. We firmly believe that, given the frequency that midurethral slings are placed without concomitant procedures, perioperative guidelines around this surgery should be evidence-based. Our hope is that this study provides one of the steps toward that goal. Editorial CommentUrologyVol. 75Issue 6PreviewWhile the use of preoperative antibiotic prophylaxis has been extensively studied and guidelines have been established by both the AUA and CMS, the use of postoperative antibiotic treatment has not been firmly established. We often use a “gut feeling” that is likely influenced by previous anecdotal outcomes experienced personally or by a colleague. This study raises an excellent question of adverse effects from postoperative antibiotic use of 3-day duration vs limiting antimicrobial agents to a solitary preoperative dose for patients undergoing midurethral sling surgery for the treatment of SUI. Full-Text PDF