Abstract
We would like to express our appreciation for Zygoura and associates' letter. It is encouraging to note that the authors actually agree with all of our caveats (detailed in the discussion section of the paper) concerning the use of accelerated corneal cross-linking (CXL) protocols in clinical practice. And we do indeed agree that revisions of CXL parameters should be implemented cautiously, with safety uppermost in mind. Evaluation of Corneal Stromal Demarcation Line Depth Following Standard and a Modified-Accelerated Collagen Cross-linking ProtocolAmerican Journal of OphthalmologyVol. 159Issue 1PreviewKymionis and associates published recently their results on high-fluence cross-linking (CXL) for progressive keratoconus.1 They have analyzed the corneal stromal demarcation line depth after CXL with 9 mW/cm2 of ultraviolet A irradiation for 14 minutes compared to standard Dresden protocol-based CXL with 3 mW/cm2 for 30 minutes. The authors did not observe any significant difference in corneal stromal demarcation line depth between the 2 groups and concluded that their modified-accelerated CXL protocol provides the same treatment depth as the classic Dresden CXL protocol, and it could possibly substitute for classic CXL regarding its efficacy. Full-Text PDF
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
