Abstract

We would like to thank Dr. Hurlstone and his colleagues for his discerning comments about the place of high-magnification chromoscopic colonoscopy (HMCC) and endoscopic ultrasonography in establishing the indication for endoscopic mucosal resection (EMR) for early colonic neoplasia. As mentioned by Hurlstone et al., many publications, including Western papers, have assessed the feasibility, reproducibility, and safety of EMR in the treatment of colonic polyps. EMR is currently regarded as a curative method of treatment for well-differentiated colonic cancer limited to the mucosa or invading less than one-third of the submucosa (sm1). In assessing the results with this method, our study was specifically designed to analyze both local recurrences and the risk of distant metastases after EMR procedures carried out exclusively in patients with early colorectal cancer.

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