Abstract

I want to thankDrs Brigo and Olivofor their interest in our recent paper “A scoping review on cannabidiol therapy in tuberous sclerosis: Current evidence and perspectives for future development [1].” I would like to take this the opportunity to respond to the concerns raised in the letter about the randomized controlled trial (RCT) evaluating the use of cannabidiol (CBD) in tuberous sclerosis (TSC), which was extensively discussed in the scoping review [2]. I agree with the general premise of their thoughtful letter that readers must critically assess the evidence supporting the use of add-on CBD for treating TSC-associated seizures before starting routinely prescribing it.

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