Abstract
Article history: Received 17 August 2015 Accepted 20 August 2015 Available online 25 August 2015 statin dose-dependently worsen insulin sensitivity by reducing plasma levels of adiponectin and increased the risk of type 2 diabetes in humans [6,7]. Andwefirst reported that losartan compensated theuntoward effect of simvastatin on insulin sensitivity when combined [3]. In addition to lowering LDL cholesterol further, ezetimibe reduced visceral fat with beneficial effects on adiponectin and insulin resistance. Indeed, experimental studies demonstrated that ezetimibe improves
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