Reply to a Comment Paper on the Published Paper by Canta, A. et al: "Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity"-Antioxidants 2020, 9, 594.

Annalisa Canta,Cristina Meregalli,Virginia Rodriguez-Menendez,Alessia Chiorazzi,Norberto Oggioni,Giulia Fumagalli,Guido Cavaletti,Jacques Näsström,Laura Monza,Eleonora Pozzi,Valentina A Carozzi,Paola Marmiroli

doi:10.3390/antiox9090807

Annalisa Canta, Cristina Meregalli + Show 10 more

Open Access

https://doi.org/10.3390/antiox9090807

Copy DOI

Abstract

The comments sent by Stehr, Lundstom and Karlsson with reference to our article "Calmangafodipir reduces sensory alterations and prevents intraepidermal nerve fiber loss in a mouse model of oxaliplatin-induced peripheral neurotoxicity" are very interesting, since they suggest possible mechanisms of action of the compound, which might contribute to its protective action [...].

Highlights

This approach was prompted by the clinical observation of its neuroprotective activity in oxaliplatin-treated patients, based on patient reported outcome (PRO) measures
The comments sent by Stehr
which might contribute to its protective action

Summary

Introduction

This approach was prompted by the clinical observation of its neuroprotective activity in oxaliplatin-treated patients, based on patient reported outcome (PRO) measures.

Results

Conclusion