Reply of the Authors: Smoking, alcohol, and coffee consumption and pregnancy loss: a Mendelian randomization investigation

Abstract

We appreciate the comments from Dr. Al-Lami and Echegaray et al. We have shared some concerns and further clarified some points raised by them in this letter. Smoking, alcohol, and coffee consumption and pregnancy loss: a Mendelian randomization investigationFertility and SterilityVol. 118Issue 6PreviewTo the Editor: (This work aims to implement the knowledge between the risk of abortions and factors such as coffee.) We have read with great interest the article entitled “Smoking, alcohol and coffee consumption and pregnancy loss: a Mendelian randomization investigation” by Yuan et al. (1), published in the journal “Fertility and Sterility.” This article is an evident example of the importance of care regarding the consumption of certain substances during pregnancy, displaying evidence of an association between smoking and an increased risk of pregnancy loss. Full-Text PDF Smoking, alcohol, and coffee consumption and pregnancy loss: a Mendelian randomization investigationFertility and SterilityVol. 118Issue 6PreviewTo the Editor: I read, with interest, the findings presented by Yuan et al. (1) in their Mendelian randomization study. In their study, smoking, but not moderate alcohol or coffee consumption, was associated with increased odds of pregnancy loss; however, they did not explain the pathophysiology behind this association (1). In this letter, I will briefly explain some of the deleterious effects of smoking exposure during pregnancy and its link to pregnancy loss. I will also highlight some points that need further clarification in the study by Yuan et al. Full-Text PDF