Reply of the Authors: Asymmetric dimethylorginine levels and carotid intima-media thickness in obese patients with polycystic ovary syndrome

Abstract

Verit and Vural have raised several concerns regarding our manuscript which was concerned with asymmetric dimethyl arginine (ADMA) and intima-media thickness (IMT) levels in PCOS. Among their suggestions and concerns was that the body mass index (BMI) issue should be taken into consideration. In the study, we accepted obesity as a BMI >27 kg/m2, as previously adopted by many authors. Unfortunately, there were two subjects in the PCOS group and one in the control group who had normal BMIs. However, this situation could have no significant effect on ADMA or IMT levels, because the mean and the median BMI levels were >27 kg/m2. Furthermore, if this discrepancy had affected ADMA or IMT levels, it would probably have caused unexpected findings in other parameters, such as homocysteine, fasting insulin levels, and C-reactive protein, but it did not. We think that the authors' other concerns regarding the presentation of our data or our preferences for the editing of the manuscript are subjective and do not make significant scientific contribution to the issue. Asymmetric dimethylorginine levels and carotid intima-media thickness in obese patients with polycystic ovary syndromeFertility and SterilityVol. 92Issue 1PreviewTo the Editor: Full-Text PDF Open Archive