Abstract
In the present study, replication of flow-through microfilters in the newly developed microfluidic lab-on-a-chip for blood typing by microinjection molding process was experimentally investigated. As a precise replication of the microfilters was required in order to effectively filter out agglutinated red blood cells, the effects of important processing conditions on the replication of the flow-through microfilters were investigated. By using a mold insert fabricated by a nickel electroplating process and a newly designed mold base, microinjection molding experiments were carried out. A three-dimensional solid model reconstruction method was proposed with the help of specific features characterizing the geometry of microfilters, and accordingly, the feature values of the replicated microfilters were measured by a noncontact optical measurement system. So reconstructed solid modeling result was then used to investigate the effects of various processing conditions, such as a flow rate, a mold temperature, and a packing pressure. Amongst the processing conditions investigated in the present study, the flow rate was found to be the most important one.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.