Abstract
The effects of infection with sacbrood virus (SBV) on larval and adult honeybees fed or injected with virus and maintained in the laboratory were determined by recording mortality, monitoring infectivity tests serologically, and identifying the sites of virus replication. Although SBV caused severe cytopathological effects in nearly all larval tissues, minimal damage was observed in most adult tissues in which the virus replicated. Serial transmission of SBV through adult worker bees was associated with precipitous mortality.
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