Abstract
Background: Treatment of depigmented skin is an unmet medical need. Objective: Melanocytes or stem cells thereof residing in the outer root sheath (ORS) of hair follicles might be used to repigment skin. Methods: After de-epidermisation, autologous ORS cell solutions were applied to 5 patients with vitiligo and 1 with leucoderma. Results: Stable repigmentation in a variable percentage was documented in all the patients. Conclusion: Applying ORS-derived melanocytes is a promising technology to improve autologous melanocyte transplantation.
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