Abstract

Materials and methods 32 patients with schizophrenia (ICD-10) without exacerbation of psychotic symptoms and with marked depression (CDSS score >6). All patients were on stabile medication for at least 4 weeks before and throughout the rTMS treatment. 15 Hz rTMS at 100% of MT was administered over the left dorsolateral prefrontal cortex. The Neuro-MS stimulator (Ivanovo, Russia) with figure-eight coil was used for 5-20 sessions within a three-week period. Each session consisted of 20 6-second trains with 1 minute intervals (1800 stimuli per session). Patients were assessed weekly by CDSS, HAMD, CGI, PANSS and battery of cognitive tests.

Highlights

  • TMS is a safe stimulation technique of the brain with antidepressive activity, but there are limited data in clinical psychiatry on application of rTMS in schizophrenia

  • International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here.

  • The aim of our study was to estimate the effect of rTMS for depression in schizophrenia

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Summary

Introduction

TMS is a safe stimulation technique of the brain with antidepressive activity, but there are limited data in clinical psychiatry on application of rTMS in schizophrenia. Nikita Maslenikov*, Eduard Tsukarzi and Sergey Mosolov Address: Department for treatment of mental disorders, Moscow Research Institute of Psychiatry, Moscow, Russia * Corresponding author from International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour Thessaloniki, Greece.

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