Abstract

A recent paper published in BMC Genomics suggests that retrotransposition may be active in the human gut parasite Entamoeba histolytica. This adds to our knowledge of the various types of repetitive elements in parasitic protists and the potential influence of such elements on pathogenicity.See research article http://www.biomedcentral.com/1471-2164/11/321

Highlights

  • A recent paper published in BMC Genomics suggests that retrotransposition may be active in the human gut parasite Entamoeba histolytica

  • Repetitive elements fall into three broad classes

  • Simple repeats can change in copy number, but do not move to new locations; DNA ‘cut-and-paste’ transposons are able to ‘jump’ to a new location; and retroposons move via an RNA intermediate, leaving an intact retroposon at the original location

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Summary

Introduction

A recent paper published in BMC Genomics suggests that retrotransposition may be active in the human gut parasite Entamoeba histolytica. Locations, of repetitive elements can alter the structures of proteins, influence gene expression and affect chromosome segregation and karyotypes. The numbers of simple repeats and transposons in the genomes of parasitic protists vary considerably, with estimates of the proportion of repetitive DNA in

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