Repeat Self-Harm Following Hospital-Presenting Intentional Drug Overdose among Young People-A National Registry Study.

Caroline Daly,Paul Corcoran,Darren M Ashcroft,Katrina Witt,Ella Arensman,Eve Griffin,Elaine Mcmahon,Roger T Webb

doi:10.3390/ijerph17176159

Abstract

Background: The incidence of hospital-presenting self-harm peaks among young people, who most often engage in intentional drug overdose (IDO). The risk of self-harm repetition is high among young people and switching methods between self-harm episodes is common. However, little is known about their patterns of repetition and switching following IDO. This study aimed to investigate repeat self-harm and method-switching following hospital-presenting IDO among young people. Methods: Data from the National Self-Harm Registry Ireland on hospital-presenting self-harm by individuals aged 10–24 years during 2009–2018 were examined. Cox proportional hazards regression models with associated hazard ratios (HRs), survival curves and Poisson regression models with risk ratios (RRs), were used to examine risk factors for repetition and method-switching. Results: During 2009–2018, 16,800 young people presented following IDO. Within 12 months, 2136 young people repeated self-harm. Factors associated with repetition included being male (HR = 1.13, 95% CI: 1.03–1.24), aged 10–17 years (HR = 1.29, 95% CI: 1.18–1.41), consuming ≥ 50 tablets (HR = 1.27, 95% CI: 1.07–1.49) and taking benzodiazepines (HR = 1.67, 95% CI: 1.40–1.98) or antidepressants (HR = 1.36, 95% CI: 1.18–1.56). The cumulative risk for switching method was 2.4% (95% CI: 2.2–2.7). Method-switching was most likely to occur for males (RR = 1.36; 95% CI: 1.09–1.69) and for those who took illegal drugs (RR = 1.63; 95% CI: 1.19–2.25). Conclusion: Young males are at increased risk of repeat self-harm and method-switching following IDO and the type and quantity of drugs taken are further indicators of risk. Interventions targeting IDO among young people are needed that ensure that mental health assessments are undertaken and which address access to drugs.

Highlights

The highest rates of self-harm are consistently seen among young people, and several countries have reported increases in youth self-harm in recent years [1,2,3,4,5,6,7,8,9].These trends are of concern, considering the association between self-harm and increased risk of suicide in young people, with repeated self-harm further elevating this risk [10]
These patterns—together with increasing trends in the use of methods with high potential lethality among young people [3]—are concerning as switching to a more lethal method in repeat self-harm is a significant predictor of suicide [26]. This and other research recommend that all young people who present to hospital following self-harm should receive a mental health assessment [23,59], in line with best practice guidelines [51,60]
Information on the source of tablets taken in intentional drug overdose (IDO) is not currently collected by the National Self-Harm Registry Ireland (NSHRI) and it is unknown as to whether or not the individual was prescribed these drugs. This national study examined the risk of repeat self-harm following IDO in young people, with a particular focus on patterns of method-switching

Summary

Introduction

The highest rates of self-harm (regardless of suicidal intent) are consistently seen among young people, and several countries have reported increases in youth self-harm in recent years [1,2,3,4,5,6,7,8,9].These trends are of concern, considering the association between self-harm and increased risk of suicide in young people, with repeated self-harm further elevating this risk [10]. The highest rates of self-harm (regardless of suicidal intent) are consistently seen among young people, and several countries have reported increases in youth self-harm in recent years [1,2,3,4,5,6,7,8,9]. The risk of self-harm repetition is high among young people. Compared to other methods of self-harm, IDO is associated with a lower risk of repetition. The incidence of hospital-presenting self-harm peaks among young people, who most often engage in intentional drug overdose (IDO). The risk of self-harm repetition is high among young people and switching methods between self-harm episodes is common. This study aimed to investigate repeat self-harm and method-switching following hospital-presenting IDO among young people. The cumulative risk for switching method was 2.4% (95% CI: 2.2–2.7)

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Conclusion