Abstract
It is known that the abnormal metabolism of tryptophan is caused by feeding a diet containing 6-aminonicotinamide. However, when rats were fed with a diet containing a large amount of nicotinic acid or nicotinamide, no aggravation of tryptophan metabolism was observed. We found that nicotinamide and nicotinic acid completely repaired the disturbance of tryptophan metabolism caused by 6-aminonicotinamide.
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