Abstract
Oral contraceptives (OCs) are used by millions of women and have proven to be very effective in contraception. To a large extent as a consequence of the cardiovascular side effects, in recent years the oestrogen concentration has been reduced and the type of progestagen has been changed. The more recent OCs are presently referred to as second and third generation, for which however the definitions are not uniform. Most commonly the second generation refers to OCs with approximately 30-35 µg ethinyloestradiol and the progestagen levonorgestrel, and the third generation to OCs with the progestagens desogestrel or gestodene and sometimes also norgestimate. Monophasic and multiphasic OCs are frequently not distinguished.
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