Abstract
Dental tissue engineering (TE) is undergoing significant modifications in dental treatments. TE is based on a triad of stem cells, signaling molecules, and scaffolds that must be understood and calibrated with particular attention to specific dental sectors. Renewable and eco-friendly carbon-based nanomaterials (CBMs), including graphene (G), graphene oxide (GO), reduced graphene oxide (rGO), graphene quantum dots (GQD), carbon nanotube (CNT), MXenes and carbide, have extraordinary physical, chemical, and biological properties. In addition to having high surface area and mechanical strength, CBMs have greatly influenced dental and biomedical applications. The current study aims to explore the application of CBMs for dental tissue engineering. CBMs are generally shown to have remarkable properties, due to various functional groups that make them ideal materials for biomedical applications, such as dental tissue engineering.
Highlights
Tissue engineering (TE) and nanomaterials (NM) in dentistry have modified perspectives and medical actions
From 1980 to 1990 [2,3], new membranes emerged with the potential to improve guided tissue regeneration (GTR) in dentistry, and autologous platelet concentrates (PRP and PRF) with membranes for restoration
The effectiveness of mesoporous bioactive glass nanoparticle potency (MBN)/graphene man dental pulp stem cells differentiation waspotency investigated in research
Summary
Tissue engineering (TE) and nanomaterials (NM) in dentistry have modified perspectives and medical actions. Guided bone loss in oral surgery can be considered the beginning of new techniques based on three main elements of tissue engineering: stem cells, media, and signaling molecules [2]. Carbon-based nanomaterials are in the spotlight of biomedical research They have established a prime position, ranging from drug delivery to tissue engineering [3,4]. Graphene and carbon nanotubes(CNTs) are among the nano carbon-based materials used in biomedical and clinical research, due to their unique characteristics, including low toxicity, high solubility, strong inertness, high specific surface areas, abundant edge sites, and versatility [5]. Surface functionalization of graphene-based nanomaterials (GBnMs) with diverse bioactive and bioinert molecules facilitates their extensive application for implant and bone scaffold improvements [10], subsequently increasing the potential of bone integration and long-term implant success. This review study aims to survey the applications, advantages, and disadvantages of eco-friendly and renewable GBnMs in implantology and scaffold improvements
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