Abstract
Renal tubular absorption of amino acids is the central topic of this chapter. However, one should not forget that renal transport of amino acids includes more than merely absorption of filtered amino acids from the tubular fluid. Like the cells of many other organs the tubule cells take up amino acids also directly from the (peritubular) blood [3, 34, 89, 98; review: 113] (see top of Fig. 1). Only the cells of the early proximal tubule may be provided with amino acids absorbed from the lumen for their metabolism [105]. Tubule cells situated more distally in the nephron adjoin a tubular fluid which is nearly empty of the majority of the amino acids [29, 105, 106, 113]; here peritubular uptake becomes essential (see top of Fig. 1).
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